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Semaglutide, more commonly known by the brand names Ozempic, Rybelsus, and Wegovy is a glucagon-like peptide-1 (GLP-1) agonist that has been used for several years in the management of type 2 diabetes mellitus (T2DM)

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Key takeaways Semaglutide heartburn and acid reflux are possible, but not among the most common side effects of Ozempic and Wegovy

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DOI: 10.1056/NEJMoa2416394

This is why you are usually told to take it on an empty stomach, 30 to 60 minutes before breakfast